Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.58 |
| ▸ | MTOR | P42345 | 17/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29183799 | 0.89 | PIK3CA (0.61) | PIK3CAMTORPIK3R1PIK3CGHDAC3 | |
| SCHEMBL29183819 | 0.88 | PIK3CA (0.60) | PIK3CAMTORPIK3R1PIK3CGHDAC3 | |
| SCHEMBL29183975 | 0.88 | PIK3CA (0.58) | PIK3CAMTORPIK3R1PIK3CGHDAC3 | |
| SCHEMBL29183979 | 0.87 | HDAC1 (0.60) | PIK3CAMTORPIK3R1PIK3CGHDAC3 | |
| SCHEMBL29183992 | 0.87 | PIK3CA (0.57) | PIK3CAMTORPIK3R1PIK3CGHDAC3 | |
| SCHEMBL29183995 | 0.86 | DRD2 (0.43) | PIK3CAMTORPIK3R1PIK3CGHDAC3 | |
| SCHEMBL29183797 | 0.81 | MTOR (0.65) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL29184046 | 0.78 | PIK3CA (0.64) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL28714705 | 0.78 | DRD4 (0.49) | DRD2 | |
| SCHEMBL29183796 | 0.77 | PIK3CA (0.63) | PIK3CAMTORPIK3R1PIK3CGHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777042-A | Triazine hydroxamic acid derivative and preparation method and application thereof | 长沙医学院 | 2024-03-29 | — | — | CN | disclosed |