Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312979 | 0.86 | POLB (0.57) | POLBTDP1ALDH1A1MAPTMCL1 | |
| SCHEMBL19329183 | 0.77 | MCL1 (0.59) | POLBTDP1MCL1BAK1PRMT5 | |
| SCHEMBL2715201 | 0.77 | L3MBTL1 (0.50) | POLBTDP1ALDH1A1MAPTMCL1 | |
| SCHEMBL12113233 | 0.76 | MAPK8 (0.50) | POLBTDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL1313799 | 0.76 | HSD17B10 (0.49) | POLBTDP1ALDH1A1MAPTMCL1 | |
| SCHEMBL7405624 | 0.75 | GABRP (0.58) | POLBTDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL1680783 | 0.75 | ALDH1A1 (0.49) | POLBTDP1ALDH1A1MCL1KDM4E | |
| SCHEMBL17560242 | 0.75 | POLB (0.44) | POLBTDP1ALDH1A1MAPTMCL1 | |
| SCHEMBL14806689 | 0.75 | POLB (0.44) | POLBTDP1ALDH1A1MAPTMCL1 | |
| SCHEMBL5119859 | 0.75 | ALDH1A1 (0.49) | POLBTDP1ALDH1A1MCL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069514-B | Antibacterial compound and application thereof | 结核病药物开发全球联盟公司 | 2023-12-29 | — | — | CN | disclosed |