Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CCL2 | P13500 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769455 | 0.91 | BRD4 (0.49) | BRD4CCL2AADATMEN1KMT2A | |
| SCHEMBL29557464 | 0.91 | BRD4 (0.49) | BRD4CCL2AADATMEN1KMT2A | |
| SCHEMBL26017423 | 0.91 | BRD4 (0.49) | BRD4CCL2AADATMEN1KMT2A | |
| SCHEMBL8292971 | 0.77 | GPR3 (0.53) | BRD4CCL2LMNAMAPTKDM4E | |
| SCHEMBL7235289 | 0.77 | EGFR (0.47) | BRD4CCL2AADATMEN1KMT2A | |
| SCHEMBL17974970 | 0.76 | MEN1 (0.49) | AADATMEN1KMT2ALMNAGAA | |
| SCHEMBL29956246 | 0.75 | MEN1 (0.42) | AADATMEN1KMT2ALMNAGAA | |
| SCHEMBL1105797 | 0.75 | HDAC4 (0.50) | BRD4CCL2AADATOPRM1OPRK1 | |
| SCHEMBL29925103 | 0.75 | HDAC4 (0.50) | BRD4CCL2AADATOPRM1OPRK1 | |
| SCHEMBL5321137 | 0.74 | AADAT (0.46) | AADATMEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117615762-A | Combination therapy | 米拉蒂治疗股份有限公司 | 2024-02-27 | — | — | CN | disclosed |