SCHEMBL2918517

SCHEMBL2918517

C=Cc1cccc(OC(C)=O)c1OC(C)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.56
PTPN1 P18031 1/20 0.45
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 5/20 0.44
KMT2A Q03164 4/20 0.44
MAPT P10636 3/20 0.44
POLB P06746 2/20 0.44
BLM P54132 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
GAA P10253 1/20 0.44
APEX1 P27695 1/20 0.44
RECQL P46063 1/20 0.44
MEN1 O00255 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
HPGD P15428 3/20 0.43
PTGS2 P35354 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17417579 0.90 KDM4E (0.54) MAPK1ALDH1A1KDM4EKMT2AMAPT
SCHEMBL5241671 0.84 MAPK1 (0.57) MAPK1PTPN1ALDH1A1KDM4EKMT2A
SCHEMBL9426682 0.84 MAPK1 (0.45) MAPK1PTPN1ALDH1A1KDM4EKMT2A
SCHEMBL30706195 0.84 PTGS2 (0.52) MAPK1ALDH1A1KDM4EKMT2ABLM
SCHEMBL58004 0.84 PTGS2 (0.52) MAPK1ALDH1A1KDM4EKMT2ABLM
SCHEMBL3248320 0.83 ACHE (0.54) MAPK1PTPN1ALDH1A1KDM4EKMT2A
SCHEMBL7200176 0.83 TLR2 (0.50) MAPK1PTPN1ALDH1A1KDM4EKMT2A
SCHEMBL8626853 0.83 CA1 (0.46) MAPK1ALDH1A1KDM4EKMT2AMAPT
SCHEMBL8830664 0.83 MAPK1 (0.56) MAPK1PTPN1ALDH1A1KDM4EKMT2A
SCHEMBL3916235 0.83 KDM4E (0.56) MAPK1PTPN1ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3491061-B1 EXPANDABLE POLYMERIC COMPOSITION COMPRISING A BLOCK COPOLYMER VERSALIS SPA (IT) 2022-04-27 EP claimed
EP-3491051-B1 EXPANDABLE VINYL AROMATIC COMPOSITION CONTAINING FUNCTIONALIZED ETHYLENE-VINYL ACETATE COPOLYMER VERSALIS SPA (IT) 2021-09-08 EP claimed
EP-3481891-B1 EXPANDABLE COMPOSITIONS CONTAINING AROMATIC VINYL POLYMERS HAVING SELF-EXTINGUISHING PROPERTIES AND IMPROVED PROCESSABILITY VERSALIS SPA (IT) 2020-04-08 EP claimed
CN-108129318-A The preparation method of one kind 3,4- diacetoxy styrene 上海博栋化学科技有限公司 2018-06-08 CN claimed
EP-1699850-B1 POLYMER PURIFICATION DUPONT ELECTRONIC POLYMERS L P (US) 2014-06-25 EP claimed
EP-1509551-B1 PROCESS FOR PURIFICATION OF ALKOXYSTYRENE POLYMERS DUPONT ELECTRONIC POLYMERS L P (US) 2010-07-07 EP claimed
EP-1497339-B1 ANHYDROUS, LIQUID PHASE PROCESS FOR PREPARING HYDROXYL CONTAINING POLYMERS OF ENHANCED PURITY DUPONT ELECTRONIC TECHNOLOGIES (US) 2008-07-30 EP claimed
EP-1639228-B1 METHOD FOR STIMULATING AN OILFIELD COMPRISING USING DIFFERENT SCALE-INHIBITORS RHODIA CHIMIE SA (FR) 2008-04-23 EP claimed
EP-0343986-B1 Process for the suspension polymerization of 4-acetoxystyrene and hydrolysis to 4-hydroxystyrene polymers HOECHST CELANESE CORP (US) 1996-02-28 EP claimed
EP-0475628-B1 Acrylate esters of 1,1,1-trishydroxyphenylethane HOECHST CELANESE CORP (US) 1995-02-01 EP claimed
EP-0252706-B1 PROCESS FOR THE PREPARATION OF POLY (VINYLPHENOL) FROM POLY (ACETOXYSTYRENE) HOECHST CELANESE CORPORATION (US) 1992-12-23 EP claimed
CN-108911982-A A kind of environment protection method for the styrene compound that synthesis acyloxy replaces 徐州博康信息化学品有限公司 2018-11-30 CN disclosed
CN-108129318-A The preparation method of one kind 3,4- diacetoxy styrene 上海博栋化学科技有限公司 2018-06-08 CN disclosed
CN-103664537-B Preparation method for resveratrol HUNAN KEYUAN BIO PRODUCTS CO LTD 2015-06-24 CN disclosed
CN-1934061-A Method for preparing hydroxystyrenes and acetylated derivatives thereof DU PONT (US) 2007-03-21 CN disclosed
EP-0700908-A1 1-Arylpyrimidine derivatives and pharmaceutical use thereof JAPAN ENERGY CORPORATION (JP) 1996-03-13 EP disclosed
WO-1994022929-A1 AMPHOTERIC COPOLYMER DERIVED FROM VINYLPYRIDINE & ACETOXYSTYRENE HOECHST CELANESE CORPORATION (US) 1994-10-13 WO disclosed
EP-0263632-A3 PROCESS FOR THE AMMONIUM HYDROXIDE HYDROLYSIS OF POLYMERS OF ACETOXYSTYRENE TO POLYMERS OF VINYLPHENOL CELANESE CORPORATION (US) 1989-03-15 EP disclosed
EP-0263632-A2 Process for the ammonium hydroxide hydrolysis of polymers of acetoxystyrene to polymers of vinylphenol CELANESE CORPORATION (US) 1988-04-13 EP disclosed
US-4129617-A Fluoro carbon graft copolymer and process for the production thereof JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1978-12-12 US disclosed