SCHEMBL7200176

SCHEMBL7200176

C=Cc1cccc(OC(C)=O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 1/20 0.50
ERN1 O75460 1/20 0.50
TLR1 Q15399 1/20 0.50
TLR6 Q9Y2C9 1/20 0.50
MAPK1 P28482 1/20 0.44
PTGS2 P35354 4/20 0.43
KDM4E B2RXH2 3/20 0.43
HSD17B10 Q99714 2/20 0.43
ALDH1A1 P00352 1/20 0.43
ESR1 P03372 1/20 0.43
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43
HMGB1 P09429 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
GGT1 P19440 1/20 0.43
PTGS1 P23219 1/20 0.43
BLM P54132 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3864807 0.86 ERN1 (0.68) TLR2ERN1TLR1TLR6MAPK1
SCHEMBL30706195 0.84 PTGS2 (0.52) MAPK1PTGS2KDM4EHSD17B10ALDH1A1
SCHEMBL58004 0.84 PTGS2 (0.52) MAPK1PTGS2KDM4EHSD17B10ALDH1A1
SCHEMBL2918517 0.83 MAPK1 (0.56) MAPK1PTGS2KDM4EHSD17B10ALDH1A1
SCHEMBL3248320 0.83 ACHE (0.54) TLR2ERN1TLR1TLR6MAPK1
Benzene SCHEMBL29242020 0.82 PTGS2 (0.55) MAPK1PTGS2KDM4EHSD17B10ALDH1A1
Water SCHEMBL27837589 0.82 PTGS2 (0.50) MAPK1PTGS2KDM4EHSD17B10ALDH1A1
Ethylene SCHEMBL27547726 0.82 PTGS2 (0.50) MAPK1PTGS2KDM4EHSD17B10ALDH1A1
Methane SCHEMBL27458309 0.82 PTGS2 (0.50) MAPK1PTGS2KDM4EHSD17B10ALDH1A1
SCHEMBL3628673 0.81 HTT (0.44) TLR2ERN1TLR1TLR6MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003062283-A1 AN OLEFIN POLYMERISATION TITANIUM CATALYST RELIANCE INDUSTRIES LIMITED (IN) 2003-07-31 WO disclosed