Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 7/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | DNA2 | P51530 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005567 | 0.82 | CHUK (0.45) | FBP1MAPTNPC1L3MBTL1TDP1 | |
| SCHEMBL29954778 | 0.77 | KDM4E (0.51) | PARP1MAPTTDP1 | |
| SCHEMBL15330894 | 0.76 | CNR1 (0.43) | FBP1PARP1MAPTNPC1MAPK1 | |
| SCHEMBL15332615 | 0.76 | MGAM (0.45) | PARP1MAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL15330730 | 0.75 | CNR1 (0.46) | PARP1MAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL15330507 | 0.75 | TNKS (0.47) | PARP1MAPTALDH1A1 | |
| SCHEMBL30182889 | 0.75 | FBP1 (0.36) | FBP1TDP1ALDH1A1CNR1 | |
| SCHEMBL15331586 | 0.74 | ALDH1A1 (0.48) | PARP1MAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL15332461 | 0.73 | MAPT (0.45) | MAPTNPC1TDP1ALDH1A1CNR1 | |
| SCHEMBL15333187 | 0.73 | MAPT (0.47) | MAPTNPC1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |