Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | ADA | P00813 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22559147 | 1.00 | KLKB1 (0.42) | KLKB1ADAHPGDITKOPRL1 | |
| SCHEMBL22585523 | 0.80 | OPRM1 (0.40) | HPGDITKOPRL1 | |
| SCHEMBL553831 | 0.78 | KLKB1 (0.53) | KLKB1ADAITK | |
| SCHEMBL14858160 | 0.78 | HPGD (0.36) | KLKB1HPGDITK | |
| SCHEMBL14857943 | 0.78 | CYP19A1 (0.47) | HPGDOPRL1 | |
| SCHEMBL28668460 | 0.75 | CREBBP (0.51) | KLKB1MEN1KMT2A | |
| SCHEMBL30782537 | 0.74 | LMNA (0.42) | KLKB1HPGDSRCMEN1KMT2A | |
| SCHEMBL14857483 | 0.73 | ACHE (0.43) | HPGD | |
| SCHEMBL29185684 | 0.72 | ELANE (0.38) | KLKB1ADAHPGDMEN1KMT2A | |
| SCHEMBL553163 | 0.71 | KLKB1 (0.52) | KLKB1HPGDITKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500496-A | Pyrimidine and pyridinamine compounds and their use in the treatment of diseases | 艾匹根生物技术有限公司 | 2024-02-02 | — | — | CN | disclosed |