Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28673610 | 0.89 | TSHR (0.54) | RARBDAOTSHRNAPRTMAPK1 | |
| Benzoic Acid SCHEMBL27884640 | 0.86 | RARB (0.53) | RARBDAOTSHRNAPRTMAPK1 | |
| Benzoic Acid SCHEMBL2007986 | 0.86 | CES2 (0.50) | RARBDAOTSHRNAPRTCES2 | |
| Benzoic Acid SCHEMBL247596 | 0.85 | TSHR (0.64) | RARBDAOTSHRNAPRTMAPK1 | |
| Benzoic Acid SCHEMBL27624637 | 0.84 | CES2 (0.51) | RARBDAOTSHRNAPRTCES2 | |
| Benzoic Acid SCHEMBL28954695 | 0.84 | CES2 (0.51) | RARBDAOTSHRNAPRTCES2 | |
| Benzoic Acid SCHEMBL27642010 | 0.84 | CES2 (0.51) | RARBDAOTSHRNAPRTCES2 | |
| Benzoic Acid SCHEMBL27769443 | 0.84 | ALDH1A1 (0.52) | RARBDAOTSHRNAPRTCES2 | |
| Benzoic Acid SCHEMBL28984665 | 0.84 | RARB (0.51) | RARBDAOTSHRNAPRTMAPK1 | |
| Isostearyl Alcohol SCHEMBL27482446 | 0.84 | RARB (0.51) | RARBDAOTSHRNAPRTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801140-A | Catalyst system for olefin polymerization reaction, prepolymerized catalyst composition and application | 中国石油化工股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117801139-A | Catalyst system for olefin polymerization reaction, prepolymerized catalyst composition and application | 中国石油化工股份有限公司 | 2024-04-02 | — | — | CN | disclosed |