Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511831 | 0.90 | OPRL1 (0.43) | OPRL1TSHR | |
| SCHEMBL8448522 | 0.90 | OPRL1 (0.43) | OPRL1TSHR | |
| SCHEMBL7513111 | 0.86 | OPRL1 (0.41) | OPRL1TSHR | |
| SCHEMBL8931253 | 0.85 | OPRL1 (0.50) | OPRL1DGAT1 | |
| SCHEMBL8931254 | 0.85 | OPRL1 (0.50) | OPRL1DGAT1 | |
| SCHEMBL10648240 | 0.85 | MAOA (0.39) | OPRL1HRH3TSHRHSD17B10 | |
| SCHEMBL10648245 | 0.85 | MAOA (0.39) | OPRL1HRH3TSHRHSD17B10 | |
| SCHEMBL30767887 | 0.84 | OPRL1 (0.43) | OPRL1DGAT1 | |
| SCHEMBL4650777 | 0.84 | CYP2C9 (0.48) | OPRL1DGAT1 | |
| SCHEMBL29186355 | 0.84 | OPRL1 (0.43) | OPRL1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |