Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 2/20 | 0.77 |
| ▸ | KDR | P35968 | 12/20 | 0.51 |
| ▸ | GAK | O14976 | 3/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.49 |
| ▸ | MET | P08581 | 3/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.47 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.47 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.47 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.47 |
| ▸ | TXK | P42681 | 1/20 | 0.47 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | STK16 | O75716 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050292 | 0.87 | DDR2 (0.83) | DDR2KDRPDGFRAMETRIPK2 | |
| SCHEMBL29317854 | 0.87 | DDR2 (0.83) | DDR2KDRPDGFRAMETRIPK2 | |
| SCHEMBL29317847 | 0.87 | DDR2 (1.00) | DDR2KDRPDGFRAMET | |
| SCHEMBL30050488 | 0.87 | DDR2 (1.00) | DDR2KDRPDGFRAMET | |
| SCHEMBL29318211 | 0.85 | DDR2 (0.83) | DDR2KDRPDGFRAMETSRC | |
| SCHEMBL29317860 | 0.84 | DDR2 (0.82) | DDR2KDRGAKPDGFRAMET | |
| SCHEMBL30050295 | 0.84 | DDR2 (0.82) | DDR2KDRGAKPDGFRAMET | |
| SCHEMBL29186589 | 0.84 | DDR2 (0.82) | DDR2KDRGAKPDGFRAMET | |
| SCHEMBL30051291 | 0.84 | DDR2 (0.82) | DDR2KDRBRAFPDGFRAMET | |
| SCHEMBL29186568 | 0.84 | DDR2 (0.82) | DDR2KDRBRAFPDGFRAMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239806-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CHENGDU ANTICANCER BIOSCIENCE LTD (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239806-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CHENGDU ANTICANCER BIOSCIENCE LTD (CN) | 2024-07-18 | — | — | US | disclosed |
| CN-117321036-A | phenyl-O-quinoline, quinazoline, thienopyridine, thienopyrimidine, pyrrolopyridine, pyrrolopyrimidine compounds having anticancer activity | 成都安泰康赛生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239806-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CYP27A1, CPT1A, OAT | DDR2 4341/4885KDR 4885/4885GAK 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.