Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ADA | P00813 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187787 | 0.89 | ALOX5 (0.37) | CPB2ALOX5PTGESMAPTALDH1A1 | |
| SCHEMBL29187782 | 0.84 | ALOX5 (0.34) | CPB2ALOX5PTGESGPR84THRB | |
| SCHEMBL29187788 | 0.84 | CPB2 (0.36) | CPB2ALOX5PTGESADANPC1 | |
| SCHEMBL29187783 | 0.80 | PIK3CA (0.40) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL29187781 | 0.77 | NPC1 (0.39) | CPB2ALOX5PTGESNPC1RAB9A | |
| SCHEMBL28895173 | 0.74 | MAPT (0.40) | NPC1RAB9AL3MBTL1MAPTATM | |
| SCHEMBL28639518 | 0.74 | LMNA (0.38) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL21919495 | 0.72 | KDM4E (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL21921861 | 0.68 | PTPN11 (0.40) | ALDH1A1LMNA | |
| SCHEMBL6899785 | 0.67 | CPB2 (0.58) | CPB2MAPTGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353509-B | Nitrogen-containing heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-04-12 | — | — | CN | disclosed |