Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
| ▸ | CETP | P11597 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30789024 | 0.84 | CASP3 (0.84) | CASP3ALDH1A1HSD17B10MAPK1USP2 | |
| SCHEMBL23748365 | 0.84 | CASP3 (0.84) | CASP3ALDH1A1HSD17B10MAPK1USP2 | |
| SCHEMBL30789006 | 0.83 | CASP3 (0.82) | CASP3ALDH1A1HSD17B10MAPK1USP2 | |
| SCHEMBL23748388 | 0.83 | CASP3 (0.82) | CASP3ALDH1A1HSD17B10MAPK1USP2 | |
| SCHEMBL29802067 | 0.71 | CASP3 (0.70) | CASP3ALDH1A1HSD17B10MAPTTP53 | |
| SCHEMBL26932345 | 0.71 | CASP3 (0.70) | CASP3ALDH1A1HSD17B10MAPTTP53 | |
| SCHEMBL24454913 | 0.70 | NPC1 (0.72) | CASP3ALDH1A1HSD17B10MAPTTP53 | |
| SCHEMBL2249425 | 0.70 | CASP3 (0.83) | CASP3ALDH1A1HSD17B10MAPK1USP2 | |
| SCHEMBL24710835 | 0.69 | ALDH1A1 (0.71) | CASP3ALDH1A1HSD17B10MAPK1USP2 | |
| SCHEMBL30965448 | 0.69 | CASP3 (0.81) | CASP3ALDH1A1HSD17B10MAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195084-B | Benzoxazoles and related compounds useful as modulators of chaperone mediated autophagy | 阿尔伯爱因斯坦医学院 | 2024-04-09 | — | — | CN | claimed |
| CN-113195084-B | Benzoxazoles and related compounds useful as modulators of chaperone mediated autophagy | 阿尔伯爱因斯坦医学院 | 2024-04-09 | — | — | CN | disclosed |