Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28915511 | 0.86 | BTK (0.44) | BTKIGF1RJAK2SYKHDAC4 | |
| SCHEMBL30063447 | 0.80 | BTK (0.43) | BTKJAK2SYKHDAC4WNT3A | |
| SCHEMBL23816211 | 0.80 | BTK (0.43) | BTKJAK2SYKHDAC4WNT3A | |
| SCHEMBL29418394 | 0.80 | BTK (0.48) | BTKHDAC4GPR119LCKPOLB | |
| SCHEMBL25269700 | 0.80 | BTK (0.48) | BTKHDAC4GPR119LCKPOLB | |
| SCHEMBL28915459 | 0.79 | BTK (0.42) | BTKJAK2SYKHDAC4WNT3A | |
| SCHEMBL24801058 | 0.77 | BTK (0.41) | BTKIGF1RJAK2SYKHDAC4 | |
| SCHEMBL25214221 | 0.75 | BTK (0.48) | BTKHDAC4GPR119LCK | |
| SCHEMBL29418480 | 0.75 | BTK (0.48) | BTKHDAC4GPR119LCK | |
| SCHEMBL25212569 | 0.75 | BTK (0.49) | BTKGPR119LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117616021-A | (R) -glutarimide CRBN ligands and methods of use | 百济神州有限公司 | 2024-02-27 | — | — | CN | disclosed |