Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | VSIR | Q9H7M9 | 8/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189956 | 0.97 | KCNH2 (0.37) | KCNH2VSIRCD274PDCD1DRD2 | |
| SCHEMBL29189973 | 0.97 | CD274 (0.37) | KCNH2VSIRCD274PDCD1CYP2D6 | |
| SCHEMBL29190133 | 0.91 | VSIR (0.35) | KCNH2VSIRCD274PDCD1DRD2 | |
| SCHEMBL29190058 | 0.90 | MAPT (0.39) | — | |
| SCHEMBL29190061 | 0.90 | MAPT (0.39) | — | |
| SCHEMBL29190117 | 0.90 | MAPT (0.39) | — | |
| SCHEMBL29190137 | 0.89 | KCNH2 (0.39) | KCNH2CD274PDCD1CYP2D6GRIN2B | |
| SCHEMBL29189911 | 0.89 | VSIR (0.38) | VSIRCD274PDCD1 | |
| SCHEMBL29190104 | 0.88 | S1PR1 (0.36) | VSIRCD274PDCD1 | |
| SCHEMBL29189893 | 0.88 | CD274 (0.39) | VSIRCD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |