Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190061 | 1.00 | MAPT (0.39) | MAPTL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL29190117 | 1.00 | MAPT (0.39) | MAPTL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL29189956 | 0.90 | KCNH2 (0.37) | L3MBTL1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL29189973 | 0.90 | CD274 (0.37) | L3MBTL1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL29189886 | 0.90 | KCNH2 (0.36) | — | |
| SCHEMBL29189979 | 0.89 | L3MBTL1 (0.35) | L3MBTL1ATMALDH1A1KDM4EKMT2A | |
| SCHEMBL29189977 | 0.89 | L3MBTL1 (0.35) | L3MBTL1ATMALDH1A1KDM4EKMT2A | |
| SCHEMBL29190133 | 0.87 | VSIR (0.35) | — | |
| SCHEMBL29190137 | 0.87 | KCNH2 (0.39) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL29189911 | 0.85 | VSIR (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |