Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189955 | 1.00 | MDM2 (0.31) | MDM2CLK1SMN1; SMN2EHMT1RPS6KA2 | |
| SCHEMBL29190137 | 0.90 | KCNH2 (0.39) | RPS6KA2PDCD1CD274 | |
| SCHEMBL29190106 | 0.89 | MDM2 (0.34) | MDM2 | |
| SCHEMBL29190109 | 0.89 | MDM2 (0.34) | MDM2 | |
| SCHEMBL29189973 | 0.88 | CD274 (0.37) | PDCD1VSIRCD274 | |
| SCHEMBL29189956 | 0.87 | KCNH2 (0.37) | PDCD1VSIRCD274 | |
| SCHEMBL29189886 | 0.87 | KCNH2 (0.36) | PDCD1VSIRCD274 | |
| SCHEMBL29190133 | 0.86 | VSIR (0.35) | PDCD1VSIRCD274 | |
| SCHEMBL29190166 | 0.86 | VSIR (0.37) | CLK1SMN1; SMN2PDCD1VSIRCD274 | |
| SCHEMBL29189912 | 0.86 | CD274 (0.39) | PDCD1VSIRCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |