Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.30 |
| ▸ | CBLB | Q13191 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190080 | 0.89 | VSIR (0.36) | PDCD1CD274VSIRESR1ESR2 | |
| SCHEMBL29189974 | 0.87 | CD274 (0.34) | PDCD1CD274VSIR | |
| SCHEMBL29189971 | 0.87 | CD274 (0.34) | PDCD1CD274VSIR | |
| SCHEMBL29190022 | 0.87 | VSIR (0.36) | PDCD1CD274VSIR | |
| SCHEMBL29190015 | 0.86 | CBLB (0.35) | PDCD1CD274VSIRCBLB | |
| SCHEMBL29190126 | 0.85 | VSIR (0.33) | VSIRESR1ESR2 | |
| SCHEMBL29189933 | 0.84 | S1PR1 (0.33) | VSIRESR1ESR2S1PR1S1PR3 | |
| SCHEMBL24818912 | 0.82 | VSIR (0.39) | PDCD1CD274VSIRESR1ESR2 | |
| SCHEMBL30152682 | 0.82 | VSIR (0.39) | PDCD1CD274VSIRESR1ESR2 | |
| SCHEMBL29189886 | 0.81 | KCNH2 (0.36) | PDCD1CD274VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |