Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 9/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.33 |
| ▸ | CBLB | Q13191 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152682 | 1.00 | VSIR (0.39) | VSIRESR1ESR2PDCD1CD274 | |
| SCHEMBL30152612 | 0.89 | VSIR (0.40) | VSIRESR1ESR2PDCD1CD274 | |
| SCHEMBL24818947 | 0.89 | VSIR (0.40) | VSIRESR1ESR2PDCD1CD274 | |
| SCHEMBL30153065 | 0.88 | VSIR (0.42) | VSIRESR1ESR2PDCD1CD274 | |
| SCHEMBL24821901 | 0.88 | VSIR (0.42) | VSIRESR1ESR2PDCD1CD274 | |
| SCHEMBL24820049 | 0.88 | VSIR (0.42) | VSIRPDCD1CD274HPGD | |
| SCHEMBL24818878 | 0.87 | VSIR (0.40) | VSIRESR1ESR2PDCD1CD274 | |
| SCHEMBL24820720 | 0.87 | VSIR (0.41) | VSIRPDCD1CD274HPGD | |
| SCHEMBL24819923 | 0.87 | VSIR (0.42) | VSIRESR1ESR2PDCD1CD274 | |
| SCHEMBL30152561 | 0.87 | VSIR (0.42) | VSIRESR1ESR2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |