Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.40 |
| ▸ | CBLB | Q13191 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152749 | 0.86 | CBLB (0.43) | C1RHSD11B1CBLBNOTUM | |
| SCHEMBL24819869 | 0.86 | CBLB (0.43) | C1RHSD11B1CBLBNOTUM | |
| SCHEMBL29190036 | 0.85 | CBLB (0.36) | C1RHSD11B1CBLBMET | |
| SCHEMBL24819899 | 0.77 | CBLB (0.39) | HSD11B1CBLBP2RX7 | |
| SCHEMBL29190151 | 0.77 | S1PR1 (0.34) | HSD11B1CBLBL3MBTL1ESR1 | |
| SCHEMBL24818731 | 0.77 | NPC1 (0.40) | HSD11B1CBLBL3MBTL1ESR1 | |
| SCHEMBL30153115 | 0.76 | CBLB (0.40) | C1RHSD11B1CBLBP2RX7CYP1A2 | |
| SCHEMBL29189897 | 0.76 | CBLB (0.40) | C1RHSD11B1CBLBP2RX7CYP1A2 | |
| SCHEMBL29190059 | 0.76 | CETP (0.37) | HSD11B1CBLB | |
| SCHEMBL24818728 | 0.74 | SCN9A (0.38) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |