Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | IL1B | P01584 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190042 | 1.00 | IDH1 (0.34) | IDH1CBLBIL1BS1PR1S1PR3 | |
| SCHEMBL30152844 | 0.85 | CBLB (0.38) | IDH1CBLB | |
| SCHEMBL29190130 | 0.81 | VSIR (0.33) | CBLBS1PR1 | |
| SCHEMBL29190141 | 0.78 | CBLB (0.34) | CBLB | |
| SCHEMBL29190140 | 0.77 | CNR2 (0.40) | CBLB | |
| SCHEMBL29190139 | 0.77 | CNR2 (0.40) | CBLB | |
| SCHEMBL29189982 | 0.73 | S1PR1 (0.35) | CBLBS1PR1S1PR3 | |
| SCHEMBL29189916 | 0.72 | S1PR1 (0.35) | CBLBS1PR1S1PR3 | |
| SCHEMBL24818679 | 0.72 | IDH1 (0.38) | IDH1CBLB | |
| SCHEMBL29190090 | 0.70 | CD274 (0.35) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |