Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | CBLB | Q13191 | 3/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792030 | 1.00 | MAP3K5 (0.37) | MAP3K5FABP4GSK3BDYRK1ACBLB | |
| SCHEMBL30792214 | 0.91 | MAP3K5 (0.36) | MAP3K5FABP4GSK3BDYRK1ACBLB | |
| SCHEMBL29190113 | 0.90 | MAP3K5 (0.40) | MAP3K5GSK3BDYRK1AGAA | |
| SCHEMBL30152722 | 0.88 | MAPK13 (0.35) | MAP3K5GSK3BDYRK1ACBLBGRM5 | |
| SCHEMBL24818750 | 0.82 | CBLB (0.45) | MAP3K5GSK3BDYRK1ACBLBGRM5 | |
| SCHEMBL29920612 | 0.82 | BDKRB2 (0.36) | MAP3K5GSK3BDYRK1ACBLBMAP4K1 | |
| SCHEMBL30152651 | 0.79 | CBLB (0.40) | CBLB | |
| SCHEMBL30792127 | 0.77 | CBLB (0.41) | MAP3K5CBLBCFTRGAA | |
| SCHEMBL24818846 | 0.77 | CBLB (0.41) | MAP3K5CBLBCFTRGAA | |
| SCHEMBL30963789 | 0.75 | CYP11B2 (0.35) | GSK3BDYRK1ACBLBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |