Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471045 | 0.81 | ALDH1A1 (0.36) | ACHEHIF1AKMT2AESR1SMN1; SMN2 | |
| SCHEMBL3950299 | 0.81 | TDP1 (0.35) | ACHEKMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL19543199 | 0.79 | KMT2A (0.37) | ACHEHIF1AKMT2AESR1SMN1; SMN2 | |
| SCHEMBL7181458 | 0.78 | ACHE (0.49) | ACHEHIF1AKMT2AESR1SMN1; SMN2 | |
| SCHEMBL29058048 | 0.76 | KMT2A (0.55) | ACHEHIF1AKMT2AESR1SMN1; SMN2 | |
| SCHEMBL30587343 | 0.76 | KMT2A (0.55) | ACHEHIF1AKMT2AESR1SMN1; SMN2 | |
| SCHEMBL29808566 | 0.76 | LMNA (0.33) | ACHEHIF1AKMT2AESR1SMN1; SMN2 | |
| SCHEMBL1401782 | 0.75 | HIF1A (0.41) | ACHEHIF1AKMT2AESR1SMN1; SMN2 | |
| SCHEMBL2885833 | 0.73 | HIF1A (0.44) | ACHEHIF1AKMT2AESR1SMN1; SMN2 | |
| SCHEMBL30055541 | 0.73 | HIF1A (0.39) | ACHEHIF1AKMT2AESR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2226329-B1 | Metal-containing platensimycin analogues | UNIV RUHR BOCHUM (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2226329-A1 | Metal-containing platensimycin analogues | Ruhr-Universität Bochum (DE) | 2010-09-08 | — | — | EP | disclosed |
| EP-1196436-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002424-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |