Dibenzofuran

Dibenzofuran

SCHEMBL29191982

c1ccc(-c2cccc3c2Cc2ccccc2-3)cc1.c1ccc2c(c1)oc1ccccc12

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.41
PRCP P42785 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
KDR P35968 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
ANPEP P15144 2/20 0.38
IL1RN P18510 1/20 0.38
ERAP2 Q6P179 1/20 0.38
ERAP1 Q9NZ08 1/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NQO1 P15559 1/20 0.36
ALOX5 P09917 1/20 0.36
HTR1A P08908 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28894088 0.87 ALOX5 (0.43) PNMTCA1CA2CA4CA6
SCHEMBL29401802 0.85 PNMT (0.53) PNMTPRCPKDRADORA2AADORA1
SCHEMBL29809707 0.85 PNMT (0.53) PNMTPRCPKDRADORA2AADORA1
SCHEMBL70992 0.85 PNMT (0.53) PNMTPRCPKDRADORA2AADORA1
SCHEMBL29177903 0.84 PNMT (0.44) PNMTCA1CA2CA4CA6
Bromide SCHEMBL15404509 0.83 PNMT (0.52) PNMTPRCPKDRADORA2AADORA1
SCHEMBL27718430 0.83 PNMT (0.52) PNMTPRCPKDRADORA2AADORA1
SCHEMBL20903535 0.83 ALOX5 (0.43) PNMTALOX5
SCHEMBL21514738 0.83 ALOX5 (0.43) PNMTALOX5
SCHEMBL17153422 0.82 PLA2G2A (0.35) PNMTCA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645592-B Compound and organic electroluminescent device 广东阿格蕾雅光电材料有限公司 2024-07-16 CN disclosed
CN-117645592-A Compound and organic electroluminescent device 广东阿格蕾雅光电材料有限公司 2024-03-05 CN disclosed