SCHEMBL29196001

SCHEMBL29196001

CCc1ccc(Nc2ccc(CC)c(CC)c2)cc1CC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.46
IDO1 P14902 1/20 0.41
NPSR1 Q6W5P4 1/20 0.37
MAPT P10636 2/20 0.35
GAA P10253 1/20 0.35
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
KIF11 P52732 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065362 0.79 ALDH1A1 (0.44) DHFRNPSR1MAPTGAAMTNR1B
SCHEMBL7344796 0.78 DHFR (0.36) DHFRIDO1GRIN2DGRIN3BGRIN1
SCHEMBL7344800 0.78 ALDH1A1 (0.41) DHFRIDO1ALDH1A1
SCHEMBL3026745 0.76 HSD17B10 (0.53) NPSR1MAPTALDH1A1HPGD
SCHEMBL30752 0.76 MAPT (0.43) DHFRIDO1MAPTGAAALDH1A1
SCHEMBL13373996 0.76 DHFR (0.35) DHFRIDO1MAPTGAAALDH1A1
SCHEMBL29764033 0.76 MAPT (0.43) DHFRIDO1MAPTGAAALDH1A1
SCHEMBL3026742 0.74 CYP3A4 (0.40) DHFRMAPTGAAALDH1A1
SCHEMBL29182473 0.74 MAPT (0.40) DHFRMAPTKIF11ALDH1A1HPGD
SCHEMBL29182470 0.74 PTPRB (0.41) MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed