Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344098 | 0.83 | POLB (0.38) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL395712 | 0.82 | CYP4A11 (0.42) | ALDH1A1L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL11418793 | 0.81 | NOS3 (0.38) | ALDH1A1ALOX15TDP1GAAMEN1 | |
| SCHEMBL29196001 | 0.79 | DHFR (0.46) | ALDH1A1GAAMAPTNPSR1DHFR | |
| SCHEMBL26326866 | 0.78 | ALDH1A1 (0.40) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL14035673 | 0.78 | MAPT (0.37) | ALDH1A1CYP3A4HIF1ATDP1L3MBTL1 | |
| SCHEMBL26805115 | 0.78 | MEN1 (0.48) | L3MBTL1GAAMEN1G6PDKMT2A | |
| SCHEMBL14035672 | 0.76 | MAPT (0.36) | ALDH1A1CYP3A4TDP1L3MBTL1GAA | |
| SCHEMBL11335981 | 0.76 | NR3C1 (0.40) | ALDH1A1CYP3A4THRBALOX15HIF1A | |
| SCHEMBL2550927 | 0.76 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737231-A1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INDUSTRIES, INC. (KR) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018181-A1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INDUSTRIES, INC. (KR) | 1995-07-06 | — | — | WO | disclosed |