Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676335 | 0.77 | FAAH (0.40) | FAAHHTTATMUSP2SMN1; SMN2 | |
| SCHEMBL7355266 | 0.71 | ALDH1A1 (0.37) | FAAHALDH1A1HTTATMMAPT | |
| SCHEMBL7346545 | 0.71 | ALDH1A1 (0.50) | FAAHALDH1A1ATMMAPTPOLB | |
| SCHEMBL14947703 | 0.70 | ELANE (0.35) | FAAHHSP90AA1HSP90AB1NR1H2USP2 | |
| SCHEMBL20816365 | 0.70 | — | — | |
| SCHEMBL4358478 | 0.68 | FAAH (0.59) | FAAHHSP90AA1HSP90AB1HTTATM | |
| SCHEMBL21432286 | 0.67 | KMT2A (0.48) | FAAHALDH1A1HSP90AA1HSP90AB1HTT | |
| SCHEMBL27997377 | 0.65 | USP2 (0.38) | FAAHNR1H2USP2SMN1; SMN2BCHE | |
| SCHEMBL306662 | 0.63 | HSP90AA1 (0.39) | FAAHHSP90AA1HSP90AB1NR1H2SMARCA2 | |
| SCHEMBL29471946 | 0.63 | FAAH (0.36) | FAAHHTTATMNR1H2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402124-A | Aryl sulfonamide compound and anti-influenza application thereof | 中国医学科学院医药生物技术研究所 | 2024-01-16 | — | — | CN | disclosed |