Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627018 | 0.78 | POLB (0.37) | ALDH1A1KMT2ANPSR1POLB | |
| SCHEMBL29196133 | 0.71 | FAAH (0.41) | ALDH1A1HTTATMPOLBFAAH | |
| SCHEMBL1862485 | 0.69 | LMNA (0.36) | ALDH1A1LMNAKMT2AHTTATM | |
| SCHEMBL31106153 | 0.68 | HTT (0.35) | ALDH1A1LMNAKMT2AHTTATM | |
| SCHEMBL7346545 | 0.68 | ALDH1A1 (0.50) | ALDH1A1KMT2AATMNPSR1POLB | |
| SCHEMBL28771845 | 0.64 | LMNA (0.40) | ALDH1A1LMNAKMT2AHTTATM | |
| SCHEMBL17965817 | 0.62 | CA1 (0.39) | LMNAKMT2ANPSR1POLB | |
| SCHEMBL320243 | 0.62 | CYP3A4 (0.44) | ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL3183015 | 0.62 | LMNA (0.39) | LMNAKMT2A | |
| SCHEMBL206710 | 0.62 | CYP3A4 (0.44) | ALDH1A1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009101-A1 | MERCAPTO-AMIDE DERIVATIVES AS INHIBITORS OF THE NEUTRAL ENDOPEPTIDASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-13 | — | — | WO | disclosed |