SCHEMBL29196259

SCHEMBL29196259

CCc1ccc(C(=O)Cl)c(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.47
LMNA P02545 3/20 0.47
HTT P42858 2/20 0.47
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.44
PTGS2 P35354 1/20 0.44
ALOX5 P09917 1/20 0.43
OR51E2 Q9H255 1/20 0.43
ALDH1A1 P00352 3/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LDHA P00338 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAPK1 P28482 1/20 0.42
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29196246 0.87 PPARG (0.58) PPARGPPARASMN1; SMN2LMNAHTT
SCHEMBL29196244 0.86 DRD2 (0.47) PPARASMN1; SMN2LMNAHTTKMT2A
SCHEMBL9295122 0.86 TTR (0.47) PPARGPPARASMN1; SMN2LMNAHTT
SCHEMBL5503225 0.84 PPARG (0.51) PPARGPPARASMN1; SMN2LMNAHTT
SCHEMBL25729047 0.84 PPARG (0.51) PPARGPPARASMN1; SMN2LMNAHTT
SCHEMBL5501065 0.84 PPARG (0.68) PPARGPPARASMN1; SMN2LMNAHTT
SCHEMBL29196236 0.83 PPARA (0.74) PPARGPPARAALOX5
SCHEMBL10267751 0.83 LMNA (0.50) PPARGPPARASMN1; SMN2LMNAHTT
SCHEMBL29196248 0.82 LDHA (0.50) PPARGPPARASMN1; SMN2LMNAHTT
SCHEMBL29196250 0.81 SMN1; SMN2 (0.52) PPARGPPARASMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924555-A Catalyst component, catalyst system, application of catalyst system and olefin polymerization method 中国石油化工股份有限公司 2024-04-26 CN disclosed
CN-117924556-A Spherical magnesium halide adduct and preparation method and application thereof 中国石油化工股份有限公司 2024-04-26 CN disclosed