SCHEMBL2919635

SCHEMBL2919635

O=C1Cc2ccccc2ON1.[Na]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.46
MAOB P27338 2/20 0.46
AHR P35869 2/20 0.45
PDK2 Q15119 1/20 0.45
TDP2 O95551 2/20 0.42
CASP3 P42574 1/20 0.42
CASP7 P55210 1/20 0.42
CASP9 P55211 1/20 0.42
CASP6 P55212 1/20 0.42
CASP8 Q14790 1/20 0.42
MAP3K14 Q99558 1/20 0.42
CYP1A2 P05177 1/20 0.39
NPC1 O15118 1/20 0.35
MAPK13 O15264 1/20 0.35
MAPK12 P53778 1/20 0.35
MAPK11 Q15759 1/20 0.35
MAPK14 Q16539 1/20 0.35
OXTR P30559 1/20 0.35
CYP2A6 P11509 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408741 0.98 MAOA (0.48) MAOAMAOBAHRPDK2TDP2
SCHEMBL6937 0.98 MAOA (0.48) MAOAMAOBAHRPDK2TDP2
Hydrochloric Acid SCHEMBL5625931 0.96 MAOA (0.46) MAOAMAOBAHRPDK2TDP2
SCHEMBL9249507 0.87 MAOA (0.43) MAOAMAOBAHRPDK2TDP2
Phenol SCHEMBL5504361 0.87 MAOB (0.39) MAOAMAOBAHRPDK2TDP2
Piperidine SCHEMBL11313946 0.87 MAOA (0.39) MAOAMAOBAHRPDK2TDP2
Carbamic Acid SCHEMBL15477883 0.87 MAOA (0.39) MAOAMAOBAHRPDK2TDP2
Isothiocyanate SCHEMBL9846811 0.87 MAOA (0.39) MAOAMAOBAHRPDK2TDP2
SCHEMBL1773313 0.81 MAOA (0.34) MAOAMAOBAHRPDK2TDP2
SCHEMBL28738530 0.81 MAOA (0.34) MAOAMAOBAHRPDK2TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314755-B1 Ultraviolet radiation absorbents for thermoplastic polymers and methods of producing the same TAKEMOTO OIL & FAT CO LTD (JP) 2010-09-08 EP disclosed
EP-1438352-B1 LOW COLOR, LOW SODIUM BENZOXAZINONE UV ABSORBERS AND PROCESS FOR MAKING SAME CYTEC TECH CORP (US) 2010-05-26 EP disclosed
US-6774232-B2 FOR USE IN HIGH TRANSPARENCY APPLICATIONS; TO PREVENT DEGRADATION CAUSED BY SUNLIGHT AND OTHER SOURCES OF ULTRAVIOLET (UV) RADIATION OF POLYMERIC MATERIALS CYTEC TECHNOLOGY CORP. 2004-08-10 US disclosed
US-6774232-B2 FOR USE IN HIGH TRANSPARENCY APPLICATIONS; TO PREVENT DEGRADATION CAUSED BY SUNLIGHT AND OTHER SOURCES OF ULTRAVIOLET (UV) RADIATION OF POLYMERIC MATERIALS CYTEC TECHNOLOGY CORP. 2004-08-10 US disclosed
EP-1438352-A1 LOW COLOR, LOW SODIUM BENZOXAZINONE UV ABSORBERS AND PROCESS FOR MAKING SAME Cytec Technology Corp. (US) 2004-07-21 EP disclosed
US-20030096889-A1 Low color, low sodium benzoxazinone UV absorbers and process for making same CYTEC TECHNOLOGY CORP. 2003-05-22 US disclosed
US-20030096889-A1 Low color, low sodium benzoxazinone UV absorbers and process for making same CYTEC TECHNOLOGY CORP. 2003-05-22 US disclosed
WO-2003035735-A1 LOW COLOR, LOW SODIUM BENZOXAZINONE UV ABSORBERS AND PROCESS FOR MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2003-05-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030096889-A1 Low color, low sodium benzoxazinone UV absorbers and process for making same XDH, SI, CA4 MAOA 231/4885MAOB 705/4885AHR 925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.