Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.68 |
| ▸ | ALPL | P05186 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874728 | 0.83 | SMN1; SMN2 (0.72) | MAPTALPLRAB9APOLBNPC1 | |
| SCHEMBL29444429 | 0.82 | SMN1; SMN2 (0.56) | MAPTALPLRAB9APOLBNPC1 | |
| SCHEMBL29197211 | 0.81 | ACR (0.52) | MAPTALPLRAB9APOLBNPC1 | |
| SCHEMBL1414008 | 0.80 | MAPT (1.00) | MAPTALPLRAB9APOLBNPC1 | |
| SCHEMBL2631731 | 0.80 | MAPT (1.00) | MAPTALPLRAB9APOLBNPC1 | |
| SCHEMBL2524441 | 0.80 | ALPL (0.76) | MAPTALPLRAB9APOLBNPC1 | |
| SCHEMBL855912 | 0.80 | ALPL (0.76) | MAPTALPLRAB9APOLBNPC1 | |
| SCHEMBL646099 | 0.80 | GAA (1.00) | MAPTALPLRAB9APOLBNPC1 | |
| SCHEMBL4788746 | 0.79 | GAA (0.75) | MAPTALPLRAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL1314014 | 0.79 | GAA (0.97) | MAPTALPLRAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886821-A | Nitrogen-containing condensed ring derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-113754587-B | Phenylpyrazole compound and application thereof | 沈阳药科大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-113754587-A | Phenylpyrazole compound and application thereof | 沈阳药科大学 | 2021-12-07 | — | — | CN | disclosed |