Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596643 | 0.87 | MEN1 (0.43) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL29197221 | 0.83 | ALDH1A1 (0.45) | KDM4ELMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL13779864 | 0.76 | MAPT (0.46) | KDM4ELMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL29197230 | 0.76 | ALDH1A1 (0.41) | LMNASMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL28474988 | 0.76 | TSHR (0.53) | KDM4ELMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL31692885 | 0.72 | ALDH1A1 (0.50) | KDM4ELMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL28470561 | 0.72 | MEN1 (0.53) | KDM4EPOLBKMT2AHSD17B10MEN1 | |
| SCHEMBL20240592 | 0.72 | NPSR1 (0.55) | KDM4ELMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL28369997 | 0.70 | LMNA (0.54) | LMNASMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL1572278 | 0.70 | ALDH1A1 (0.60) | KDM4ESMN1; SMN2POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940425-A | HER2 mutation inhibitors | 阿雷生物药品公司 | 2024-04-26 | — | — | CN | disclosed |