Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29197218 | 0.87 | KDM4E (0.43) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL13779864 | 0.85 | MAPT (0.46) | MEN1KMT2AERN1ALDH1A1MAPT | |
| SCHEMBL5693941 | 0.80 | LMNA (0.54) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL29269278 | 0.80 | MAPK1 (0.54) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL23275859 | 0.78 | MAPT (0.49) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7161701 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28683817 | 0.78 | VCAM1 (0.54) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL1572278 | 0.78 | ALDH1A1 (0.60) | ERN1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL20958154 | 0.75 | MAPT (0.45) | MEN1KMT2AERN1ALDH1A1MAPT | |
| SCHEMBL28474988 | 0.75 | TSHR (0.53) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250199-B | Dihydropyridone P1 as factor XIA inhibitor | 百时美施贵宝公司 | 2021-07-16 | — | — | CN | disclosed |