SCHEMBL29197239

SCHEMBL29197239

CC(C)Oc1cc(O)c(C(=O)O)c(O)c1[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
COMT P21964 4/20 0.39
PDK1 Q15118 1/20 0.39
PKM P14618 1/20 0.38
XDH P47989 1/20 0.36
CYP19A1 P11511 2/20 0.36
TPMT P51580 1/20 0.35
CDK2 P24941 1/20 0.34
EP300 Q09472 1/20 0.34
HIF1A Q16665 1/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 2/20 0.33
FFAR1 O14842 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29196799 0.84 PKM (0.50) CA1CA2COMTPKMTPMT
SCHEMBL29196797 0.82 MYC (0.42) CA1CA2COMTPKMXDH
SCHEMBL30454482 0.80 CA1 (0.41) CA1CA2PKML3MBTL1ALDH1A1
SCHEMBL9617118 0.76 CA1 (0.51) CA1CA2PKMTPMTCDK2
SCHEMBL19193965 0.74 COMT (0.41) CA1CA2COMTPKMTPMT
SCHEMBL29196806 0.73 CTSV (0.46) COMTCYP19A1
SCHEMBL19199670 0.71 PRKCE (0.47) CA1CA2PKMTPMTCDK2
SCHEMBL19193391 0.69 CA1 (0.37) CA1CA2COMTPKMTPMT
SCHEMBL1459278 0.69 GAA (0.45) CA1CA2PDK1XDHKDM4E
SCHEMBL20589188 0.69 IRAK4 (0.49) PDK1PKMCDK2KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283588-A 4-alkoxy substituted 2, 6-dihydroxybenzoic acid right-embedded alcohol or fenchyl alcohol ester compound and pharmaceutical application thereof 南京医科大学 2023-06-23 CN disclosed