SCHEMBL30454482

SCHEMBL30454482

CCOc1cc(O)c(C(=O)O)c(O)c1[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MAPT P10636 4/20 0.39
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
PKM P14618 1/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
ALDH1A1 P00352 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GRM8 O00222 3/20 0.36
GRM4 Q14833 3/20 0.36
ACMSD Q8TDX5 1/20 0.36
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29196797 0.85 MYC (0.42) CA1CA2PKM
SCHEMBL29196799 0.84 PKM (0.50) CA1CA2MAPTPKMALDH1A1
SCHEMBL29196806 0.81 CTSV (0.46) MAPTMEN1KMT2A
SCHEMBL29197239 0.80 CA1 (0.41) CA1CA2PKMALDH1A1L3MBTL1
SCHEMBL10898948 0.78 GRIN2D (0.43) MAPTTSHRPKMMEN1KMT2A
SCHEMBL9617118 0.76 CA1 (0.51) CA1CA2MAPTHSD17B10PKM
SCHEMBL28589207 0.75 KMT2A (0.41) MAPTTSHRMEN1KMT2AALDH1A1
SCHEMBL19199670 0.74 PRKCE (0.47) CA1CA2MAPTPKMMEN1
SCHEMBL28573288 0.74 KMT2A (0.39) MAPTMEN1KMT2AALDH1A1KDM4C
SCHEMBL9274760 0.72 TSHR (0.52) MAPTTSHRHSD17B10PKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283588-A 4-alkoxy substituted 2, 6-dihydroxybenzoic acid right-embedded alcohol or fenchyl alcohol ester compound and pharmaceutical application thereof 南京医科大学 2023-06-23 CN disclosed