Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | TSHR | P16473 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.80 |
| ▸ | PGR | P06401 | 3/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.80 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.80 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.80 |
| ▸ | CNR1 | P21554 | 3/20 | 0.80 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.80 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.80 |
| ▸ | DRD3 | P35462 | 3/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Econazole SCHEMBL18916745 | 0.91 | IDO1 (0.86) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL18916744 | 0.91 | IDO1 (0.86) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL34498 | 0.90 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL7602990 | 0.90 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL20482166 | 0.90 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL29440264 | 0.90 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL34499 | 0.90 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL7602993 | 0.90 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL18614748 | 0.88 | IDO1 (0.88) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL18614749 | 0.88 | IDO1 (0.88) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250121068-A1 | BIFUNCTIONAL MOLECULES AS PROTEASOME STIMULATORS FOR IMPROVED TARGETED PROTEIN DEGRADATION, AND THEIR USES AS TARGETED BOOSTING DEGRADERS (TARBODS) | BOOSTER THERAPEUTICS GMBH (DE) | 2025-04-17 | — | — | US | disclosed |
| EP-4398941-A1 | BIFUNCTIONAL MOLECULES AS PROTEASOME STIMULATORS FOR IMPROVED TARGETED PROTEIN DEGRADATION, AND THEIR USES AS TARGETED BOOSTING DEGRADERS (TARBODS) | Booster Therapeutics GmbH (DE) | 2024-07-17 | — | — | EP | disclosed |
| CN-117940167-A | Bifunctional molecules as proteasome stimulators for improved targeted protein degradation and their use as targeted enhancing degradation agents (TARBOD) | 博思德医疗科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023036936-A1 | BIFUNCTIONAL MOLECULES AS PROTEASOME STIMULATORS FOR IMPROVED TARGETED PROTEIN DEGRADATION, AND THEIR USES AS TARGETED BOOSTING DEGRADERS (TARBODS) | BOOSTER THERAPEUTICS GMBH (DE) | 2023-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250121068-A1 | BIFUNCTIONAL MOLECULES AS PROTEASOME STIMULATORS FOR IMPROVED TARGETED PROTEIN DEGRADATION, AND THEIR USES AS TARGETED BOOSTING DEGRADERS (TARBODS) | PSMB1, PSMD1, PSMB2 | IDO1 3305/4885CYP2C9 4498/4885CYP3A4 3593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.