Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Econazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 14/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.86 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.86 |
| ▸ | LMNA | P02545 | 3/20 | 0.86 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.86 |
| ▸ | PGR | P06401 | 3/20 | 0.86 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.86 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.86 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.86 |
| ▸ | CNR1 | P21554 | 3/20 | 0.86 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.86 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.86 |
| ▸ | DRD3 | P35462 | 3/20 | 0.86 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.86 |
| ▸ | MC3R | P41968 | 3/20 | 0.86 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.86 |
| ▸ | NPY2R | P49146 | 2/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Econazole SCHEMBL18916744 | 1.00 | IDO1 (0.86) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL20482166 | 0.93 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL7602990 | 0.93 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL34499 | 0.93 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL7602993 | 0.93 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL34498 | 0.93 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL29440264 | 0.93 | IDO1 (1.00) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL29197519 | 0.91 | IDO1 (0.80) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL18614748 | 0.91 | IDO1 (0.88) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 | |
| Econazole SCHEMBL18614749 | 0.91 | IDO1 (0.88) | IDO1CYP2C9CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834533-B2 | Polymer composition | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2023-12-05 | — | — | US | disclosed |
| EP-4095162-A1 | APPLICATION OF AND PREPARATION METHOD FOR CATIONIC POLYMER MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER | Soochow University (CN) | 2022-11-30 | — | — | EP | disclosed |
| CN-113456531-A | Composition for external application to skin | 株式会社LG生活健康 | 2021-10-01 | — | — | CN | disclosed |
| CN-106999403-B | Composition for external application to skin | 株式会社LG生活健康 | 2021-07-06 | — | — | CN | disclosed |
| CN-106999404-B | Composition for external application to skin | 株式会社LG生活健康 | 2021-07-02 | — | — | CN | disclosed |
| US-20210122848-A1 | POLYMER COMPOSITION | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2021-04-29 | — | — | US | disclosed |
| CN-112708007-A | Polymer composition, method for producing same, film-forming agent, and cosmetic composition | 株式会社LG生活健康 | 2021-04-27 | — | — | CN | disclosed |
| CN-107001530-B | Polymer and method of making same | 株式会社LG化学 | 2020-10-20 | — | — | CN | disclosed |
| US-10808060-B2 | Polymer | LG CHEM, LTD. (KR) | 2020-10-20 | — | — | US | disclosed |
| EP-3225640-B1 | POLYMER | LG CHEMICAL LTD (KR) | 2020-09-09 | — | — | EP | disclosed |
| US-10316125-B2 | Polymer | LG CHEM, LTD. (KR) | 2019-06-11 | — | — | US | disclosed |
| US-10023664-B2 | Polymer | LG CHEM, LTD. (KR) | 2018-07-17 | — | — | US | disclosed |
| US-20170342179-A1 | POLYMER | LG CHEM, LTD. (KR) | 2017-11-30 | — | — | US | disclosed |
| US-20170342180-A1 | POLYMER | LG CHEM, LTD. (KR) | 2017-11-30 | — | — | US | disclosed |
| US-20170327614-A1 | POLYMER | LG CHEM, LTD. (KR) | 2017-11-16 | — | — | US | disclosed |
| EP-3235838-A1 | POLYMER | LG Chem, Ltd. (KR) | 2017-10-25 | — | — | EP | disclosed |
| EP-3225648-A1 | POLYMER | LG Chem, Ltd. (KR) | 2017-10-04 | — | — | EP | disclosed |
| EP-3225640-A1 | POLYMER | LG Chem, Ltd. (KR) | 2017-10-04 | — | — | EP | disclosed |
| US-20170275398-A1 | POLYMER | LG CHEM, LTD. (KR) | 2017-09-28 | — | — | US | disclosed |
| EP-3176188-A1 | POLYMER | LG Chem, Ltd. (KR) | 2017-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327614-A1 | POLYMER | CUTA, KRT18, AQP3 | IDO1 3934/4885CYP2C9 4268/4885CYP3A4 4196/4885 |
| US-20210122848-A1 | POLYMER COMPOSITION | CUTA, FRG1, PFN1 | IDO1 3044/4885CYP2C9 2893/4885CYP3A4 4097/4885 |
| US-20170342180-A1 | POLYMER | PHYKPL, LCP1, PUF60 | IDO1 4432/4885CYP2C9 3692/4885CYP3A4 3593/4885 |
| US-10808060-B2 | Polymer | CUTA, KRT18, AQP3 | IDO1 3934/4885CYP2C9 4268/4885CYP3A4 4196/4885 |
| US-10316125-B2 | Polymer | CUTA, KRT18, AQP3 | IDO1 3934/4885CYP2C9 4268/4885CYP3A4 4196/4885 |
| US-20170342179-A1 | POLYMER | CUTA, KRT18, AQP3 | IDO1 3934/4885CYP2C9 4268/4885CYP3A4 4196/4885 |
| US-11834533-B2 | Polymer composition | CUTA, FRG1, PFN1 | IDO1 3044/4885CYP2C9 2893/4885CYP3A4 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.