Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TGM1 | P22735 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31140036 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL3266258 | 0.83 | HRH3 (0.43) | CKS1BSKP1SKP2KMT2A | |
| SCHEMBL31140038 | 0.80 | AKR1C3 (0.50) | CKS1BSKP1SKP2 | |
| SCHEMBL1728874 | 0.80 | AKR1C3 (0.50) | CKS1BSKP1SKP2 | |
| SCHEMBL29197813 | 0.79 | EPHX1 (0.45) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL30112569 | 0.79 | EPHX1 (0.45) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL6276733 | 0.79 | DGAT1 (0.49) | ALDH1A1TSHRCKS1BSKP1SKP2 | |
| SCHEMBL6478335 | 0.79 | HDAC1 (0.61) | ALDH1A1TSHRTGM2TGM1MEN1 | |
| SCHEMBL3025692 | 0.78 | CKS1B (0.60) | CTSKCKS1BSKP1SKP2 | |
| SCHEMBL21564567 | 0.78 | CKS1B (0.60) | ALDH1A1TSHRCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940414-A | Compounds for targeting IRAK4 protein degradation | 渤健马萨诸塞州股份有限公司 | 2024-04-26 | — | — | CN | disclosed |