Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.68 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.68 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | PLAU | P00749 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31187400 | 0.87 | PLAU (0.60) | SIRT2SIRT1SIRT3ALDH1A1CYP3A4 | |
| SCHEMBL7524753 | 0.84 | ALDH1A1 (0.69) | SIRT2SIRT1SIRT3ALDH1A1CYP3A4 | |
| SCHEMBL9702779 | 0.81 | LCK (0.56) | SIRT2SIRT1SIRT3ALDH1A1CYP3A4 | |
| SCHEMBL3117113 | 0.81 | MAPK13 (0.67) | SIRT2ALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL29352988 | 0.81 | ALDH1A1 (0.91) | SIRT2SIRT1SIRT3ALDH1A1CYP3A4 | |
| SCHEMBL39488 | 0.81 | ALDH1A1 (0.91) | SIRT2SIRT1SIRT3ALDH1A1CYP3A4 | |
| SCHEMBL9513153 | 0.81 | ALDH1A1 (0.91) | SIRT2SIRT1SIRT3ALDH1A1CYP3A4 | |
| SCHEMBL21446854 | 0.80 | PLAU (0.79) | PLAUNPC1RAB9AMEN1KMT2A | |
| SCHEMBL546633 | 0.79 | CES2 (0.68) | SIRT2SIRT1SIRT3ALDH1A1CYP3A4 | |
| SCHEMBL29462782 | 0.79 | CES2 (0.68) | SIRT2SIRT1SIRT3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117902997-A | Amine antioxidant and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-04-19 | — | — | CN | disclosed |