Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25631844 | 1.00 | DDB1 (0.57) | DDB1CRBNGPR119TGFBR1HTR1A | |
| SCHEMBL30981483 | 0.98 | DDB1 (0.56) | DDB1CRBNGPR119 | |
| SCHEMBL25631853 | 0.94 | DDB1 (0.55) | DDB1CRBNGPR119 | |
| SCHEMBL21965415 | 0.92 | DDB1 (0.67) | DDB1CRBNGPR119 | |
| SCHEMBL29199173 | 0.91 | DDB1 (0.64) | DDB1CRBNGPR119TGFBR1 | |
| SCHEMBL30981069 | 0.88 | DDB1 (0.63) | DDB1CRBNGPR119TGFBR1 | |
| SCHEMBL25631901 | 0.88 | DDB1 (0.60) | DDB1CRBN | |
| SCHEMBL25631810 | 0.88 | DDB1 (0.60) | DDB1CRBNGPR119 | |
| SCHEMBL30883435 | 0.87 | DRD2 (0.54) | DDB1CRBN | |
| SCHEMBL27225200 | 0.87 | DRD2 (0.54) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014147-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250320205-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320205-A1 | STAT6 DEGRADERS | STAT6, STAT1, STAT5B | DDB1 3708/4885CRBN 1751/4885GPR119 1588/4885 |
| US-20260014147-A1 | STAT6 DEGRADERS | STAT6, NCOR1, CBR1 | DDB1 3708/4885CRBN 133/4885GPR119 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.