Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931284 | 0.86 | ALDH1A1 (0.32) | GRIK1GRIK2ALDH1A1CES2CES1 | |
| SCHEMBL197706 | 0.77 | ALDH1A1 (0.37) | ALDH1A1CES2CES1FFAR3HDAC3 | |
| SCHEMBL7931089 | 0.77 | ALDH1A1 (0.37) | ALDH1A1CES2CES1FFAR3HDAC3 | |
| SCHEMBL800038 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2ALDH1A1CES2CES1 | |
| SCHEMBL811730 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2ALDH1A1CES2CES1 | |
| SCHEMBL5423161 | 0.76 | GRIK1 (0.41) | GRIK1GRIK2ALDH1A1CES2CES1 | |
| SCHEMBL4246377 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2ALDH1A1CES2CES1 | |
| SCHEMBL27682930 | 0.75 | GRIK1 (0.38) | GRIK1GRIK2ALDH1A1CES2CES1 | |
| SCHEMBL21635680 | 0.74 | GRIK1 (0.53) | GRIK1GRIK2ALDH1A1CES2CES1 | |
| SCHEMBL21635654 | 0.74 | GRIK1 (0.53) | GRIK1GRIK2ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946340-A | Temperature-sensitive color-changing hydrogel and preparation method and application thereof | 西北农林科技大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946340-A | Temperature-sensitive color-changing hydrogel and preparation method and application thereof | 西北农林科技大学 | 2024-04-30 | — | — | CN | disclosed |