Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999841 | 0.92 | DNM1 (0.38) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3249856 | 0.89 | DNM1 (0.41) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL21748447 | 0.86 | DNM1 (0.38) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2928875 | 0.83 | DNM1 (0.43) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL28367317 | 0.81 | DNM1 (0.35) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2925069 | 0.81 | DNM1 (0.48) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL16784960 | 0.76 | — | — | |
| SCHEMBL21748456 | 0.76 | DNM1 (0.48) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL16705799 | 0.75 | NFKB1 (0.35) | DNM1ALDH1A1TSHRNFKB1 | |
| SCHEMBL29047704 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117434038-A | Novel method for rapid nondestructive measurement of platelet function | 南方医科大学 | 2024-01-23 | — | — | CN | disclosed |