Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199431 | 0.82 | CES2 (0.51) | HPGDMAPTRAB9AKMT2ALMNA | |
| SCHEMBL30866417 | 0.82 | CES2 (0.51) | HPGDMAPTRAB9AKMT2ALMNA | |
| SCHEMBL9418310 | 0.73 | RXFP1 (0.79) | HPGDMAPTRAB9AKMT2ALMNA | |
| SCHEMBL51509 | 0.73 | RXFP1 (0.79) | HPGDMAPTRAB9AKMT2ALMNA | |
| SCHEMBL12378791 | 0.71 | LMNA (0.60) | HPGDMAPTRAB9AKMT2ALMNA | |
| SCHEMBL31612201 | 0.71 | MAPT (0.63) | HPGDMAPTRAB9AKMT2ALMNA | |
| SCHEMBL22446521 | 0.70 | NOTUM (0.54) | HPGDMAPTRAB9AKMT2ALMNA | |
| SCHEMBL30301343 | 0.70 | RXFP1 (0.55) | HPGDRXFP1ALDH1A1SMN1; SMN2KDM4E | |
| Ethyne SCHEMBL8195983 | 0.69 | RXFP1 (0.73) | HPGDMAPTRAB9AKMT2ALMNA | |
| SCHEMBL9563117 | 0.69 | RXFP1 (0.61) | HPGDMAPTRAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |