Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | MGMT | P16455 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14499669 | 0.98 | HPGD (0.50) | HPGDNPSR1GAARAB9ANPC1 | |
| SCHEMBL26349189 | 0.88 | MGMT (0.42) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL26349201 | 0.86 | KDM4E (0.49) | HPGDNPSR1GAATSHRMAPK1 | |
| SCHEMBL8862940 | 0.84 | GAA (0.60) | HPGDNPSR1GAARAB9ANPC1 | |
| SCHEMBL8862746 | 0.84 | GAA (0.60) | HPGDNPSR1GAARAB9ANPC1 | |
| SCHEMBL8862856 | 0.84 | GAA (0.60) | HPGDNPSR1GAARAB9ANPC1 | |
| SCHEMBL7519591 | 0.84 | GAA (0.60) | HPGDNPSR1GAARAB9ANPC1 | |
| SCHEMBL14763361 | 0.84 | GAA (0.73) | GAAMAPTALDH1A1MGMTKMT2A | |
| SCHEMBL17440158 | 0.84 | GAA (0.73) | GAAMAPTALDH1A1MGMTKMT2A | |
| SCHEMBL30455730 | 0.83 | RAB9A (0.37) | HPGDNPSR1GAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322777-A | Heteroaryl and heterocyclyl compounds | 西吉隆医疗股份有限公司 | 2023-06-23 | — | — | CN | disclosed |