Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199650 | 0.83 | HPGD (0.49) | RAB9ANPC1KMT2AMGMTHPGD | |
| SCHEMBL14499669 | 0.81 | HPGD (0.50) | RAB9ANPC1KMT2AHPGDNPSR1 | |
| SCHEMBL30456011 | 0.79 | RAB9A (0.37) | RAB9ANPC1ATMKMT2AMEN1 | |
| SCHEMBL26349189 | 0.78 | MGMT (0.42) | RAB9ANPC1KMT2AMEN1MGMT | |
| SCHEMBL26349215 | 0.77 | ALDH1A1 (0.38) | ATMMGMTHPGDNPSR1GAA | |
| SCHEMBL30458078 | 0.75 | MGMT (0.42) | MGMTABCG2CA1CA2CA4 | |
| SCHEMBL26349179 | 0.75 | MGMT (0.42) | MGMTABCG2CA1CA2CA4 | |
| SCHEMBL15096386 | 0.74 | CYP1B1 (0.53) | NPC1KMT2AMEN1 | |
| SCHEMBL30455266 | 0.74 | CYP1B1 (0.53) | NPC1KMT2AMEN1 | |
| SCHEMBL30459062 | 0.74 | CYP1B1 (0.53) | NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192468-A2 | HETEROARYL AND HETEROCYCLYL COMPOUNDS | Sigilon Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |