Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | ME2 | P23368 | 1/20 | 0.34 |
| ▸ | ME1 | P48163 | 1/20 | 0.34 |
| ▸ | ME3 | Q16798 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29990537 | 0.91 | GPR119 (0.42) | PRMT5 | |
| SCHEMBL24670657 | 0.91 | GPR119 (0.42) | PRMT5 | |
| SCHEMBL30112336 | 0.82 | AAK1 (0.43) | CHRM4DGAT1MCHR1PRMT5RET | |
| SCHEMBL29197698 | 0.82 | AAK1 (0.43) | CHRM4DGAT1MCHR1PRMT5RET | |
| SCHEMBL23459570 | 0.81 | PRMT5 (0.41) | DGAT1MCHR1KCNH2PRMT5RET | |
| SCHEMBL29872807 | 0.81 | PRMT5 (0.41) | DGAT1MCHR1KCNH2PRMT5RET | |
| SCHEMBL29197741 | 0.81 | DGAT1 (0.43) | CHRM4DGAT1CETPKCNH2PRMT5 | |
| SCHEMBL30112428 | 0.81 | DGAT1 (0.43) | CHRM4DGAT1CETPKCNH2PRMT5 | |
| SCHEMBL24881518 | 0.80 | DGAT1 (0.48) | DGAT1KCNH2PRMT5RET | |
| SCHEMBL25190189 | 0.79 | IDH1 (0.53) | DGAT1MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916231-A | Compounds for inhibiting or degrading target proteins, compositions comprising the same, methods of making and methods of using the same | 纽力克斯治疗公司 | 2024-04-19 | — | — | CN | disclosed |