Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16832166 | 0.86 | NQO2 (0.51) | KDM4EPLA2G2ANR4A2CHEK1ABL1 | |
| SCHEMBL24619653 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1HPGDPLA2G2ANR4A2 | |
| SCHEMBL16833198 | 0.85 | NQO2 (0.49) | KDM4EPLA2G2ANR4A2ABL1 | |
| SCHEMBL24619171 | 0.83 | L3MBTL1 (0.52) | KDM4EALDH1A1HPGDPLA2G2ANR4A2 | |
| SCHEMBL29199714 | 0.79 | PSMD14 (0.49) | KDM4EALDH1A1PLA2G2ANR4A2MAPT | |
| SCHEMBL29727189 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1HPGDPLA2G2AL3MBTL1 | |
| SCHEMBL24619257 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1HPGDPLA2G2AL3MBTL1 | |
| SCHEMBL24619696 | 0.75 | KDM4E (0.36) | KDM4EALDH1A1HPGDPLA2G2AL3MBTL1 | |
| SCHEMBL29727245 | 0.75 | KDM4E (0.36) | KDM4EALDH1A1HPGDPLA2G2AL3MBTL1 | |
| SCHEMBL2905571 | 0.74 | NQO2 (0.42) | KDM4EALDH1A1PLA2G2ANR4A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120077038-A | Substituted 6- (pyrimidin-4-yl) quinoline compounds as cyclin dependent kinase inhibitors | 百济神州(苏州)生物科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-117946077-A | Substituted 6- (pyrimidin-4-yl) quinoline compounds as cyclin dependent kinase inhibitors | 百济神州(北京)生物科技有限公司 | 2024-04-30 | — | — | CN | disclosed |