Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200117 | 0.91 | MAOB (0.38) | MAOBALDH1A1MAPTSMN1; SMN2ALDH2 | |
| SCHEMBL29200103 | 0.89 | GSTP1 (0.35) | MAOBALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL29200110 | 0.87 | MAOB (0.35) | MAOBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29200101 | 0.87 | MAOB (0.35) | MAOBALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29200105 | 0.86 | MAOB (0.37) | MAOBALDH1A1MAPTSMN1; SMN2ALDH2 | |
| SCHEMBL29200092 | 0.85 | MAOB (0.42) | MAOBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29200114 | 0.84 | ALDH1A1 (0.37) | MAOBALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29200119 | 0.79 | KDM4E (0.35) | MAOBSMN1; SMN2CYP19A1KDM4EHSD17B10 | |
| SCHEMBL7131700 | 0.67 | KLK5 (0.40) | MAOBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7077595 | 0.67 | MAOB (0.38) | MAOBNPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991694-B | Chiral sulfone compound and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2024-03-19 | — | — | CN | disclosed |