Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200117 | 0.94 | MAOB (0.38) | MAOBKDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL29200101 | 0.90 | MAOB (0.35) | MAOBKDM4EHPGDNPC1RAB9A | |
| SCHEMBL29200092 | 0.88 | MAOB (0.42) | MAOBKDM4EHPGDMAPTNPC1 | |
| SCHEMBL29200090 | 0.87 | NR3C2 (0.38) | MAOBKDM4EHPGDCYP3A4MAPT | |
| SCHEMBL29200103 | 0.87 | GSTP1 (0.35) | MAOBHPGDCYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL29200105 | 0.84 | MAOB (0.37) | MAOBKDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL29200114 | 0.82 | ALDH1A1 (0.37) | MAOBKDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29200119 | 0.77 | KDM4E (0.35) | MAOBKDM4ESMN1; SMN2HTR1AHTR7 | |
| SCHEMBL7077595 | 0.69 | MAOB (0.38) | MAOBKDM4EHPGDNPC1RAB9A | |
| SCHEMBL7131700 | 0.66 | KLK5 (0.40) | MAOBKDM4EHPGDCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991694-B | Chiral sulfone compound and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2024-03-19 | — | — | CN | disclosed |