Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200117 | 0.92 | MAOB (0.38) | MAOBMAPTCYP19A1MEN1KMT2A | |
| SCHEMBL29200101 | 0.88 | MAOB (0.35) | MAOBNPC1RAB9ACYP19A1MEN1 | |
| SCHEMBL29200110 | 0.88 | MAOB (0.35) | MAOBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29200103 | 0.87 | GSTP1 (0.35) | MAOBACHEBACE1PPARGALDH1A1 | |
| SCHEMBL29200090 | 0.85 | NR3C2 (0.38) | MAOBMAPTNPC1RAB9ACYP19A1 | |
| SCHEMBL29200105 | 0.82 | MAOB (0.37) | MAOBMAPTCYP19A1MEN1KMT2A | |
| SCHEMBL29200114 | 0.81 | ALDH1A1 (0.37) | MAOBMAPTRAB9AMEN1KMT2A | |
| SCHEMBL29200119 | 0.76 | KDM4E (0.35) | MAOBCYP19A1PPARGSMN1; SMN2KDM4E | |
| SCHEMBL705946 | 0.67 | CYP19A1 (0.52) | MAOBMAPTNPC1RAB9ACYP19A1 | |
| SCHEMBL7131700 | 0.65 | KLK5 (0.40) | MAOBMAPTNPC1RAB9ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991694-B | Chiral sulfone compound and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2024-03-19 | — | — | CN | disclosed |