Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25257982 | 0.83 | BRD4 (0.47) | DRD2CYP3A4SLC6A2HTR2AHTR2C | |
| SCHEMBL28897147 | 0.82 | CYP3A4 (0.42) | DRD2CYP3A4SLC6A2HTR2AHTR2C | |
| SCHEMBL29929388 | 0.82 | CYP3A4 (0.42) | DRD2CYP3A4SLC6A2HTR2AHTR2C | |
| SCHEMBL25299441 | 0.78 | DRD2 (0.36) | DRD2CYP3A4SLC6A2HTR2AHTR2C | |
| SCHEMBL30771502 | 0.76 | HPGD (0.39) | HTTLMNAKMT2ATSHRBRD4 | |
| SCHEMBL25300843 | 0.76 | PIK3C3 (0.36) | DRD2CYP3A4SLC6A2HTR2AHTR2C | |
| SCHEMBL14678605 | 0.76 | CYP3A4 (0.35) | DRD2CYP3A4SLC6A2HTR2AHTR2C | |
| SCHEMBL28897148 | 0.75 | CYP3A4 (0.42) | DRD2CYP3A4SLC6A2HTR2AHTR2C | |
| SCHEMBL28335335 | 0.72 | CYP3A4 (0.34) | DRD2CYP3A4SLC6A2HTR2AHTR2C | |
| SCHEMBL25255375 | 0.72 | RAPGEF4 (0.40) | DRD2CYP3A4SLC6A2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638477-B | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2024-01-26 | — | — | CN | disclosed |